Volume 20, Issue 1

At the 20th Congress of ECCO, held in Berlin, Germany from February 19 to 22, 2025, we organised the 10th H-ECCO IBD Masterclass. The aims of our meeting were to discuss the histopathological aspects of Inflammatory Bowel Disease (IBD), to highlight the multidisciplinary approach to the diagnostic process – also illustrated by the similar number of pathologists and gastroenterologists in the audience – and to look towards the future.

Sophie Restellini is a familiar name to many in the ECCO Community. She serves as Director of the Center for Crohn’s and Colitis in Geneva and is an Adjunct Professor at McGill University Health Center in Montreal. In this month's Y-ECCO Interview, we delve into Sophie’s career, her connection with ECCO, her contributions to the field of IBD field and her insights into the future of IBD treatment and education.

Risankizumab versus ustekinumab for moderate-to-severe Crohn’s disease Peyrin-Biroulet L, Chapman JC, Colombel JF, et al. N Engl J Med 2024;391:213–23.

Vedolizumab to prevent postoperative recurrence of Crohn’s disease (REPREVIO): a multicentre, double-blind, randomised, placebo-controlled trial D'Haens G, Taxonera C, Lopez-Sanroman A, et al. Lancet Gastroenterol Hepatol 2025;10:26–33; DOI: 10.1016/S2468-1253(24)00317-0

A disease-associated gene desert directs macrophage inflammation through ETS2 Stankey CT, Bourges C, Haag LM et al. Nature 2024;630:447–56.

The 11th edition of the Y-ECCO Science Workshop took place during the ECCO Congress in Berlin on February 19 , 2025, providing a platform for early-career basic and translational scientists to present and discuss research with peers and senior experts. The event fostered an intellectually stimulating environment, encouraging participants to expand their knowledge and engage in advanced research challenges.