N13 Low compliance with remote monitoring of patient-reported outcomes via digital application in patients with inflammatory bowel disease

Haj Natour, O.(1)*;Ben Horin, S.(2);Lipkin, M.(3);Galper, A.(2);kopylov, U.(2);

(1)Tel-HaShomer Sheba Medical Center, Department of Gastroenterology, Ramat Gan, Israel;(2)Sheba Medical Center, Gastroenterology, Ramat Gan, Israel;(3)Sheba Medical Center, Gastroentrology, Ramat Gan, Israel;


Remote management through online web-based services can reduce healthcare utilization and improve the quality of life and treatment adherence of IBD patients compared to standard care.However, the actual compliance and durability of remote follow-up protocols in IBD have not been well studied.

Aim:To describe the compliance with mobile-app patient-reported outcomes (PRO) questionnaires in a long-term monitoring   program for IBD patients  


 Retrospective cohort study that included patients with Crohn’s Disease (CD) or ulcerative colitis (UC) treated at a tertiary center. Patients received questionnaires via the specialized smartphone app  Datos Health™.The follow-up program included the following questionnaires: IBD-control,Patient-Reported Outcomes Measurement Information System (PROMIS-10), Short IBD Questionnaire (S-IBDQ), and Patient Reported Outcome-2 (PRO 2). 


 402 IBD patients were enrolled in the program; 299 (74.4%) had CD and 103 UC (25.6%).  187 of the study patients (46.5%)  male, 16(0.04%) were naive to biological therapy, 189 (47%) received their first biological therapy. Median age as 35.68 (interquartile ratio (IQR)- 35.68-43.31) and mean disease duration 9.8 years (7-14).

SIBDQ was sent for 515 (398-577) days,20 (15-23) questionnaires were sent, response rate was 23%. After 30 days -62(15.4%) of patients were still responding, 100 days- 36(9%), 1 year- 40(11.3%).

PROMIS-10 was sent for a median of 482(365-574) days; 17(13-20) questionnaires were sent, response rate was 13%. After 30 days -27(6.7%) of patients were still responding, after 100 days- 21(5.2%) and after 1 year- 34 (8.5%).  

IBD-control was sent for a median of 515(397-584) days; 21(15-23) questionnaires were sent ,response rate was 22%. After 30 days -63 (15.7%) of patients were still responding, after 100 days- 37 (9.2%) and after 1 year- 40 (10%).

PRO 2 was sent for a median of 361(144-447) days;107(47-140) questionnaires were sent, response rate-11% After 30 days-47(11.7%), after 100 days -23(5.7%) and after 1 year -36(9%) were still responding

Figure 1: The response rate  of filled questionnaires over time

SIBDQ; Short IBD Questionnaire. PRO-2; Patient-Reported Outcomes 2.  Promis-global 10; Patient-Reported Outcomes Measurement Information System . IBD-control.


 Long-term follow-up of IBD patients with remote PRO is associated with low compliance and high withdrawal rates.Future design of such programs should accommodate patients' needs, incorporatE rapid rule-based feedback and devise a smart adaptive frequency strategy to avoid alert fatigue and increase compliance.