P258 The association between dietary quality and disease severity in Korean young adult patients with Crohn’s disease: A pilot study
Jeong, E.S.(1)*;Lee, Y.J.(2);Song, E.M.(3);Byeon, J.R.(3);Lee, A.(1);Choe , A.R.(3);Hong, J.T.(1);Park, Y.H.(3);Tae, C.H.(3);Moon, C.M.(1);Jeong, H.K.(1);Shim, K.N.(3);Jung, S.A.(3);Kim, Y.(2);Kim, S.E.(1);
(1)Ewha Womans University Mokdong Hospital, Internal medicine, Seoul, Korea- Republic Of;(2)Ewha Womans University, Nutritional Science and Food Management, Seoul, Korea- Republic Of;(3)Ewha Womans University Seoul Hospital, Internal Medicine, Seoul, Korea- Republic Of;
Although associations between various single nutrients and exacerbation of inflammatory bowel disease (IBD) have been reported, more recent attention has focused on overall dietary patterns and quality rather than a single nutrient. This study was to investigate the association of dietary inflammatory potential and dietary quality with disease severity in young adult Crohn’s disease (CD) patients.
Non-consecutive 3-day food records were investigated in 25 patients with CD aged 19-40 years. Patients with moderate or severe active disease were excluded to investigate their usual dietary habits. A survey on dietary behavior was conducted and clinical data including the disease progress were collected. To investigate potential pro-inflammatory dietary habits in a patient's usual diet, food-based index of dietary inflammatory potential score (FBDI), glycemic index (GI), and glycemic load (GL) were calculated. Diet quality was evaluated using a tool called Diet Quality Index-international (DQI).
Although most patients showed adequate caloric intake, 72% of the enrolled patients had a potential pro-inflammatory pattern identified as FBDI. The FBDI was significantly associated with intake of mixed coffee and sweeten drinks, beef, and pork (P < 0.05). Patients who had a serious clinical course such as history of surgery or the use of biologics, tended to have a higher FBDI (6.45 vs 2.44, P = 0.08), and showed a higher proportion with a low DQI (53% vs 20%, P = 0.06). Only 30% of the high FBDI group showed deep remission after 12 to 18 months of follow-up endoscopic or image study, whereas 72.7% of the low FBDI group showed deep remission (P =0.05). A significantly positive correlation was derived between FBDI and GL (r =0.452, P = 0.02).
For the care of patients with CD, it is necessary to evaluate the dietary quality as well as the total nutrient intake, and we need to educate the patients that dietary habits can affect the disease prognosis.