P788 Gender differences in consumption of processed and ultra-processed foods in Crohn’s disease patients

C. Sarbagili Shabat1,2, S. Zelber-Sagi1,3, N. Fliss Isakov1, Y. Ron1, A. Hirsch1, N. Maharshak1,2

1Tel-Aviv Medical Center, IBD Center, Department of Gastroenterology and Liver Diseases, Tel-Aviv, Israel, 2Tel-Aviv University, The Sackler Faculty of Medicine, Tel-Aviv, Israel, 3University of Haifa, School of Public Health, Haifa, Israel

Background

Consumption of processed foods is thought to be associated with Crohn’s disease (CD) pathogenesis. In Israel, CD demonstrates higher prevalence rate among men. Our aim was to examine gender differences among CD patients in the consumption of processed foods.

Methods

A post hoc analysis of a prospective validation study of a novel processed food questionnaire (PFQ) was performed in adult CD patients followed at a tertiary center in Israel. The PFQ categorises food items according to the level of processing as unprocessed or minimally processed, processed and ultra-processed foods. Demographic and clinical data were collected. Linear regression, ANOVA, t-test were performed looking at the association between disease characteristics, age, education, gender and consumption of processed foods.

Results

Sixty patients (33 men, 27 women) were included in the analysis. Mean age of participants was 29.4 ± 8.6 for men and 31.7 ± 10.2 for women. Men consumed on average more portions of processed foods per day than women (3.09 ± 2.31 vs. 1.98 ± 1.32, p = 0.023, respectively). Similar association was found for ultra-processed foods consumption, where men consumed 1.63 ± 0.75 more portions per day than women (5.77 ± 2.90 vs. 4.14 ± 2.87, p = 0.034, respectively). Disease characteristics (duration, behaviour, and activity), age and education levels were not associated with consumption of processed foods.

Conclusion

Men with CD consumed significantly more processed and ultra-processed foods compared with women, emphasising a need for dietary intervention in men if these findings are consistent in larger studies.