Peter Irving © ECCO

Dear ECCO Friends,

The purpose of e-CCO is to improve knowledge, to enhance the educational experience and to equalise access to advanced learning opportunities in IBD for our members and throughout the world. I am pleased to be able to highlight, therefore, how the e-Learning Taskforce continues to work hard to keep the e-CCO Learning site up to date with the aim of achieving these goals.

Naila Arebi © ECCO

Collaborations are the cornerstone of research studies – from inception of the idea to execution of the project, culminating in the final research goal of generating and sharing new knowledge. Information technology has transformed the way we collaborate, opening up new avenues for collaboration through enhanced remote communication between researchers as well as easier collation and sharing of research data across centres.

The PANTS study

Nicholas Kennedy © ECCO

Use of the anti-TNF alpha monoclonal antibodies infliximab and adalimumab has transformed the management of patients with refractory Crohn’s Disease. However, clinicians and patients are all too aware that anti-TNF treatment failure is common: 10%–40% of patients fail to respond to induction therapy (referred to as primary non-response: PNR), up to 40% of patients suffer secondary loss of response in the first year of therapy and approximately 10% suffer an adverse drug reaction that curtails treatment.

In faecal microbiota transplantation (FMT) for Ulcerative Colitis, Fusobacterium is associated with lack of remission, while metabolic shifts to starch degradation and short chain fatty acid production are associated with remission (FOCUS study)

Sudarshan Paramsothy © ECCO

The randomised controlled FOCUS study [1], along with other trials [2–4], suggests that FMT is effective in the treatment of patients with active Ulcerative Colitis (UC). However, the underlying microbial basis and predictors of therapeutic outcome in UC are largely unknown. We therefore performed in-depth microbial analyses on the samples collected during the FOCUS study to help identify bacterial taxonomic and functional changes associated with FMT in UC, particularly those predictive of therapeutic success or failure.

Janneke van der Woude © ECCO

During the ECCO’18 Vienna Congress the Scientific Committee cordially welcomed Michael Scharl and Sebastian Zeissig as new members.

Pieter Hindryckx © ECCO

Willem Bemelman

Position: Secretary 2018–2020

Nationality: Dutch

Born: December 17, 1958

Past ECCO Positions: 
     • Co-founder of S-ECCO
     • S-ECCO Chair
     • Chair, Surgical ECCO Guidelines on Crohn’s Disease

Isabelle Cleynen © ECCO

With the Y-ECCO Basic Science Workshop, Y-ECCO aims to give basic science, and young clinicians doing basic science or full-time researchers, a more visible platform within ECCO and the ECCO Congress. We also want to promote scientific exchange and networking among (young) basic scientists. Each edition of the workshop features two top-notch speakers and experts in their field who give state of the art overviews on the session topics and are then invited to join the discussions following oral abstract presentations by Y-ECCO Members. The two sessions of this year’s workshop focussed on “In vivo perils in IBD” and “Ex vivo promises in IBD”. 

Nuha Yassin © ECCO

Dear Y-ECCO Friends,

In our series of Y-ECCO corner interviews, we are adding a new flavour for 2018 by conducting a tandem interview with the IBD giants. Today, I am delighted to be joined by Ailsa Hart and Willem Bemelman, who are respectively a leading gastroenterologist and leading surgeon in the world of IBD. We have all heard them give tandem talks and look forward to finding out more about them in this tandem interview. Many thanks for agreeing to be interviewed, Ailsa and Willem. We’ll ask you similar questions and see if the answers are similar or different.

Nuha Yassin
Y-ECCO Interview Corner Coordinator

Nuha Yassin © ECCO

Dear Y-ECCO Friends,

This is my first Members’ Address as the newly elected Y-ECCO Chair after being a Committee Member for the past 3 years. I have succeeded Isabelle Cleynen (Leuven), who was a fantastic chair and a great friend. I had the pleasure of previously working with Tim Raine and Pieter Hindryckx, who were also exemplary in their leadership of Y-ECCO, and I am delighted to be able to keep in touch with them. Y-ECCO truly creates solid bonds and I am honoured to have been given the opportunity to work with past Committee Members and Chairs as well as the current fantastic Committee.

David Wilson © ECCO

The first International Symposium on Paediatric Inflammatory Bowel Disease (PIBD) took place in Rome in 2006 and was hosted by Salvatore Cucchiara. It was followed by the second PIBD Symposium in 2009 in Paris, hosted by Frank Ruemmele. Both were private initiatives. After a pause while plans to alternate PIBD Symposia between venues in Europe and North America were considered, the paediatric IBD Porto group of ESPGHAN took over all organisation. This resulted in the 3^rd Symposium in Rotterdam in 2014, hosted by Hankje Escher.